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Sequence Detail
ID/Version
P70424 Q61525 Q6ZPE0 (UniProt | EBI) Last sequence update: 2005-09-27
Last annotation update: 2024-05-29
Sequence
description
from provider
RecName: Full=Receptor tyrosine-protein kinase erbB-2; EC=2.7.10.1;AltName: Full=Proto-oncogene Neu;AltName: Full=Proto-oncogene c-ErbB-2;AltName: Full=p185erbB2;AltName: CD_antigen=CD340;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 1256 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Erbb2 erb-b2 receptor tyrosine kinase 2 153 132 3 29
Sequence references in MGI J:29667 Moscoso LM, et al., Synapse-associated expression of an acetylcholine receptor-inducing protein, ARIA/heregulin, and its putative receptors, ErbB2 and ErbB3, in developing mammalian muscle. Dev Biol. 1995 Nov;172(1):158-69
J:39139 Lim H, et al., Differential expression of the erbB2 gene in the periimplantation mouse uterus: potential mediator of signaling by epidermal growth factor-like growth factors. Endocrinology. 1997 Mar;138(3):1328-37
J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:203534 Kwon HS, et al., Myocilin mediates myelination in the peripheral nervous system through ErbB2/3 signaling. J Biol Chem. 2013 Sep 13;288(37):26357-71
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory