Sequence Detail

ID/Version

P70428 P70395 Q923D6 Q3TPI7 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Exostosin-2 {ECO:0000305}; EC=2.4.1.224 {ECO:0000269|PubMed:10639137};AltName: Full=Exostosin glycosyltransferase 2 {ECO:0000312|MGI:MGI:108050};AltName: Full=Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminy

Provider

SWISS-PROT

Sequence

Polypeptide 718 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ext2	exostosin glycosyltransferase 2	58	102	3	13

Sequence references in MGI

J:39672 Clines GA, et al., The structure of the human multiple exostoses 2 gene and characterization of homologs in mouse and Caenorhabditis elegans [letter]. Genome Res. 1997 Apr;7(4):359-67
J:42216 Stickens D, et al., Isolation and characterization of the murine homolog of the human EXT2 multiple exostoses gene. Biochem Mol Med. 1997 Jun;61(1):16-21
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113870 McCormick C, et al., The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate. Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):668-73
J:133353 Presto J, et al., Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation. Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4751-6