Sequence Detail

ID/Version

P70452 Q80WT8 Q3TSL5 Q3UKQ8 (UniProt | EBI)

Last sequence update: 1997-02-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Syntaxin-4;

Provider

SWISS-PROT

Sequence

Polypeptide 298 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Stx4a	syntaxin 4A (placental)	119	99	3	12

Sequence references in MGI

J:38990 Tellam JT, et al., Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4. J Biol Chem. 1997 Mar 7;272(10):6179-86
J:55848 Min J, et al., Synip: a novel insulin-regulated syntaxin 4-binding protein mediating GLUT4 translocation in adipocytes. Mol Cell. 1999 Jun;3(6):751-60
J:86138 Buxton P, et al., Identification and characterization of Snapin as a ubiquitously expressed SNARE-binding protein that interacts with SNAP23 in non-neuronal cells. Biochem J. 2003 Oct 15;375(Pt 2):433-40
J:93035 Wang CC, et al., A role of VAMP8/endobrevin in regulated exocytosis of pancreatic acinar cells. Dev Cell. 2004 Sep;7(3):359-71
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:140958 Pooley RD, et al., Murine CENPF interacts with syntaxin 4 in the regulation of vesicular transport. J Cell Sci. 2008 Oct 15;121(Pt 20):3413-21
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:146942 Fukuda N, et al., DOC2B: a novel syntaxin-4 binding protein mediating insulin-regulated GLUT4 vesicle fusion in adipocytes. Diabetes. 2009 Feb;58(2):377-84
J:161112 Ke B, et al., Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis. J Biol Chem. 2007 Jul 27;282(30):21786-97
J:178002 Bhatnagar S, et al., Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion. PLoS Genet. 2011 Oct;7(10):e1002323
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:352391 Schrauwen I, et al., Syntaxin 4 is essential for hearing in human and zebrafish. Hum Mol Genet. 2023 Mar 20;32(7):1184-1192