Sequence Detail

ID/Version

P70661 (UniProt | EBI)

Last sequence update: 1997-02-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Neurogenin-3; Short=NGN-3;AltName: Full=Helix-loop-helix protein mATH-4B; Short=mATH4B;AltName: Full=Protein atonal homolog 5;

Provider

SWISS-PROT

Sequence

Polypeptide 214 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Neurog3	neurogenin 3	39	188	3	23

Sequence references in MGI

J:38581 Sommer L, et al., neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS. Mol Cell Neurosci. 1996;8(4):221-41
J:40190 Cau E, et al., Mash1 activates a cascade of bHLH regulators in olfactory neuron progenitors. Development. 1997 APR;124(8):1611-1621
J:60642 Gradwohl G, et al., neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1607-11
J:137207 Lynn FC, et al., Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network. PLoS One. 2008;3(6):e2430
J:156329 Anderson KR, et al., Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48