Sequence Detail

ID/Version

P70671 (UniProt | EBI)

Last sequence update: 1997-02-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Interferon regulatory factor 3; Short=IRF-3;

Provider

SWISS-PROT

Sequence

Polypeptide 419 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Irf3	interferon regulatory factor 3	78	106	3	21

Sequence references in MGI

J:97662 Honda K, et al., IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature. 2005 Apr 7;434(7034):772-7
J:145466 Stetson DB, et al., Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell. 2008 Aug 22;134(4):587-98
J:178837 Perwitasari O, et al., Inhibitor of kappaB Kinase {epsilon} (IKK{epsilon}), STAT1, and IFIT2 Proteins Define Novel Innate Immune Effector Pathway against West Nile Virus Infection. J Biol Chem. 2011 Dec 30;286(52):44412-23
J:184127 Honda K, et al., Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors. Immunity. 2006 Sep;25(3):349-60
J:275220 Huai W, et al., KAT8 selectively inhibits antiviral immunity by acetylating IRF3. J Exp Med. 2019 Apr 1;216(4):772-785
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89