Sequence Detail

ID/Version

P84091 P53679 P20172 (UniProt | EBI)

Last sequence update: 2004-08-16
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=AP-2 complex subunit mu;AltName: Full=AP-2 mu chain;AltName: Full=Adaptor protein complex AP-2 subunit mu;AltName: Full=Adaptor-related protein complex 2 subunit mu;AltName: Full=Clathrin assembly protein complex 2 mu medium chain;AltName: F

Provider

SWISS-PROT

Sequence

Polypeptide 435 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ap2m1	adaptor-related protein complex 2, mu 1 subunit	61	99	4	34

Sequence references in MGI

J:28934 Ohno H, et al., Interaction of tyrosine-based sorting signals with clathrin-associated proteins. Science. 1995 Sep 29;269(5232):1872-5
J:47156 Ohno H, et al., Cloning of the gene encoding the murine clathrin-associated adaptor medium chain mu 2: gene organization, alternative splicing and chromosomal assignment. Gene. 1998 Apr 14;210(2):187-93
J:102181 Mitsunari T, et al., Clathrin adaptor AP-2 is essential for early embryonal development. Mol Cell Biol. 2005 Nov;25(21):9318-23
J:114866 Bairstow SF, et al., Type Igamma661 phosphatidylinositol phosphate kinase directly interacts with AP2 and regulates endocytosis. J Biol Chem. 2006 Jul 21;281(29):20632-42
J:201438 Marcello E, et al., Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease. J Clin Invest. 2013 Jun 3;123(6):2523-38
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89