Sequence Detail

ID/Version

P97321 (UniProt | EBI)

Last sequence update: 1997-05-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Prolyl endopeptidase FAP {ECO:0000250|UniProtKB:Q12884}; EC=3.4.21.26 {ECO:0000269|PubMed:24371721};AltName: Full=Dipeptidyl peptidase FAP {ECO:0000250|UniProtKB:Q12884}; EC=3.4.14.5 {ECO:0000269|PubMed:10629066, ECO:0000269|

Provider

SWISS-PROT

Sequence

Polypeptide 761 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fap	fibroblast activation protein	51	107	3	14

Sequence references in MGI

J:40036 Niedermeyer J, et al., Mouse fibroblast activation protein: Molecular cloning, alternative splicing and expression in the reactive stroma of epithelial cancers. Int J Cancer. 1997 MAY 2;71(3):383-389
J:48813 Niedermeyer J, et al., Mouse fibroblast-activation protein--conserved Fap gene organization and biochemical function as a serine protease. Eur J Biochem. 1998 Jun 15;254(3):650-4
J:59998 Niedermeyer J, et al., Targeted disruption of mouse fibroblast activation protein. Mol Cell Biol. 2000 Feb;20(3):1089-94
J:74135 Niedermeyer J, et al., Expression of the fibroblast activation protein during mouse embryo development. Int J Dev Biol. 2001 Apr;45(2):445-7
J:91461 Ramirez-Montagut T, et al., FAPalpha, a surface peptidase expressed during wound healing, is a tumor suppressor. Oncogene. 2004 Jul 15;23(32):5435-46
J:218666 Kraman M, et al., Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha. Science. 2010 Nov 5;330(6005):827-30