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Sequence Detail
ID/Version
P97363 P97356 (UniProt | EBI) Last sequence update: 1998-01-01
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Serine palmitoyltransferase 2 {ECO:0000305}; EC=2.3.1.50 {ECO:0000250|UniProtKB:O15270};AltName: Full=Long chain base biosynthesis protein 2; Short=LCB 2;AltName: Full=Long chain base biosynthesis protein 2a; Short=LC
Provider SWISS-PROT
Sequence
Polypeptide 560 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Sptlc2 serine palmitoyltransferase, long chain base subunit 2 22 100 4 245
Sequence references in MGI J:36511 Nagiec MM, et al., Sphingolipid synthesis: identification and characterization of mammalian cDNAs encoding the Lcb2 subunit of serine palmitoyltransferase. Gene. 1996 Oct 24;177(1-2):237-41
J:43725 Weiss B, et al., Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis. Eur J Biochem. 1997 Oct 1;249(1):239-47
J:247919 Lee SY, et al., Adipocyte-Specific Deficiency of De Novo Sphingolipid Biosynthesis Leads to Lipodystrophy and Insulin Resistance. Diabetes. 2017 Oct;66(10):2596-2609
J:255961 Chaurasia B, et al., Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism. Cell Metab. 2016 Dec 13;24(6):820-834
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory