Sequence Detail

ID/Version

P97465 Q9R213 (UniProt | EBI)

Last sequence update: 2003-01-17
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Docking protein 1;AltName: Full=Downstream of tyrosine kinase 1;AltName: Full=p62(dok);

Provider

SWISS-PROT

Sequence

Polypeptide 482 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dok1	docking protein 1	15	97	4	9

Sequence references in MGI

J:40721 Yamanashi Y, et al., Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok. Cell. 1997 Jan 24;88(2):205-11
J:52798 Jang W, et al., Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. Genome Res. 1999 Jan;9(1):53-61
J:87966 Shi N, et al., Structural basis for the specific recognition of RET by the Dok1 phosphotyrosine binding domain. J Biol Chem. 2004 Feb 6;279(6):4962-9
J:95641 Yamanashi Y, et al., Role of the rasGAP-associated docking protein p62(dok) in negative regulation of B cell receptor-mediated signaling. Genes Dev. 2000 Jan 1;14(1):11-6
J:113910 Sattler M, et al., SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL. J Biol Chem. 2001 Jan 26;276(4):2451-8
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89