Sequence Detail

ID/Version

P97480 G5E8I5 P97768 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Eyes absent homolog 3; EC=3.1.3.48 {ECO:0000269|PubMed:14628042, ECO:0000269|PubMed:14628052, ECO:0000269|PubMed:14628053};

Provider

SWISS-PROT

Sequence

Polypeptide 510 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Eya3	EYA transcriptional coactivator and phosphatase 3	36	119	3	402

Sequence references in MGI

J:38379 Xu PX, et al., Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode. Development. 1997 Jan;124(1):219-31
J:38486 Zimmerman JE, et al., Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene. Genome Res. 1997 Feb;7(2):128-41
J:52368 Borsani G, et al., EYA4, a novel vertebrate gene related to Drosophila eyes absent. Hum Mol Genet. 1999 Jan;8(1):11-23
J:86608 Rayapureddi JP, et al., Eyes absent represents a class of protein tyrosine phosphatases. Nature. 2003 Nov 20;426(6964):295-8
J:86619 Li X, et al., Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature. 2003 Nov 20;426(6964):247-54
J:113793 Ohto H, et al., Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya. Mol Cell Biol. 1999 Oct;19(10):6815-24
J:212814 Ikeda K, et al., Molecular interaction and synergistic activation of a promoter by Six, Eya, and Dach proteins mediated through CREB binding protein. Mol Cell Biol. 2002 Oct;22(19):6759-66
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89