Sequence Detail

ID/Version

P97737 Q6PE07 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Growth/differentiation factor 10; Short=GDF-10;AltName: Full=Bone morphogenetic protein 3B; Short=BMP-3B;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 476 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gdf10	growth differentiation factor 10	18	117	4	6

Sequence references in MGI

J:29417 Cunningham NS, et al., Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3. Growth Factors. 1995;12(2):99-109
J:56683 Zhao R, et al., Characterization of GDF-10 expression patterns and null mice. Dev Biol. 1999 Aug 1;212(1):68-79
J:185675 Matsumoto Y, et al., Bone morphogenetic protein-3b (BMP-3b) inhibits osteoblast differentiation via Smad2/3 pathway by counteracting Smad1/5/8 signaling. Mol Cell Endocrinol. 2012 Mar 5;350(1):78-86
J:205652 Hino J, et al., Bone morphogenetic protein-3b (BMP-3b) is expressed in adipocytes and inhibits adipogenesis as a unique complex. Int J Obes (Lond). 2012 May;36(5):725-34
J:214970 Mecklenburg N, et al., Growth and differentiation factor 10 (Gdf10) is involved in Bergmann glial cell development under Shh regulation. Glia. 2014 Oct;62(10):1713-23