Sequence Detail

ID/Version

P97868 Q3UMP7 Q4U217 Q7TT06 Q3TUM7 Q8R399 Q8BNY8 P70287 Q3TTR9 (UniProt | EBI)

Last sequence update: 2006-05-16
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase RBBP6; EC=2.3.2.27;AltName: Full=Proliferation potential-related protein;AltName: Full=Protein P2P-R;AltName: Full=RING-type E3 ubiquitin transferase RBBP6 {ECO:0000305};AltName: Full=Retinoblastoma-bindin

Provider

SWISS-PROT

Sequence

Polypeptide 1790 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rbbp6	retinoblastoma binding protein 6, ubiquitin ligase	35	98	3	26

Sequence references in MGI

J:38614 Witte MM, et al., The proliferation potential protein-related (P2P-R) gene with domains encoding heterogeneous nuclear ribonucleoprotein association and Rb1 binding shows repressed expression during terminal differentiation. Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1212-7
J:40929 Simons A, et al., PACT: cloning and characterization of a cellular p53 binding protein that interacts with Rb. Oncogene. 1997 Jan 16;14(2):145-55
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:121586 Li L, et al., PACT is a negative regulator of p53 and essential for cell growth and embryonic development. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7951-6
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:224718 Miotto B, et al., The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability. Cell Rep. 2014 Apr 24;7(2):575-87
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89