Sequence Detail

ID/Version

P98200 B2RQF2 (UniProt | EBI)

Last sequence update: 2000-05-30
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Phospholipid-transporting ATPase IB {ECO:0000305}; EC=7.6.2.1 {ECO:0000250|UniProtKB:C7EXK4};AltName: Full=ATPase class I type 8A member 2;AltName: Full=P4-ATPase flippase complex alpha subunit ATP8A2;

Provider

SWISS-PROT

Sequence

Polypeptide 1148 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Atp8a2	ATPase, aminophospholipid transporter-like, class I, type 8A, member 2	42	101	3	13

Sequence references in MGI

J:59384 Halleck MS, et al., Differential expression of putative transbilayer amphipath transporters. Physiol Genomics. 1999 Nov 11;1(3):139-50
J:185526 Xu Q, et al., P(4)-ATPase ATP8A2 acts in synergy with CDC50A to enhance neurite outgrowth. FEBS Lett. 2012 Jun 21;586(13):1803-12
J:188127 Zhu X, et al., Mutations in a P-type ATPase gene cause axonal degeneration. PLoS Genet. 2012 Aug;8(8):e1002853
J:211318 Coleman JA, et al., Phospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival. J Cell Sci. 2014 Mar 1;127(Pt 5):1138-49
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89