Sequence Detail

ID/Version

P99029 Q9QZ75 Q9QX45 (UniProt | EBI)

Last sequence update: 2002-02-21
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Peroxiredoxin-5, mitochondrial; EC=1.11.1.24 {ECO:0000269|PubMed:10679306};AltName: Full=Antioxidant enzyme B166; Short=AOEB166;AltName: Full=Liver tissue 2D-page spot 2D-0014IV;AltName: Full=PLP;AltName: Full=Peroxiredoxin V

Provider

SWISS-PROT

Sequence

Polypeptide 210 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prdx5	peroxiredoxin 5	51	106	3	9

Sequence references in MGI

J:58008 Yamashita H, et al., Characterization of human and murine PMP20 peroxisomal proteins that exhibit antioxidant activity in vitro. J Biol Chem. 1999 Oct 15;274(42):29897-904
J:58175 Knoops B, et al., Cloning and characterization of AOEB166, a novel mammalian antioxidant enzyme of the peroxiredoxin family. J Biol Chem. 1999 Oct 22;274(43):30451-8
J:61576 Lee TH, et al., Molecular cloning and characterization of the mouse peroxiredoxin V gene. Biochem Biophys Res Commun. 2000 Apr 13;270(2):356-62
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:296117 Cao Y, et al., ABHD10 is an S-depalmitoylase affecting redox homeostasis through peroxiredoxin-5. Nat Chem Biol. 2019 Dec;15(12):1232-1240
J:333123 Zhou Y, et al., Mouse peroxiredoxin V is a thioredoxin peroxidase that inhibits p53-induced apoptosis. Biochem Biophys Res Commun. 2000 Feb 24;268(3):921-7