Sequence Detail

ID/Version

Q00609 Q61332 (UniProt | EBI)

Last sequence update: 1994-02-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=T-lymphocyte activation antigen CD80;AltName: Full=Activation B7-1 antigen; Short=B7;AltName: CD_antigen=CD80;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 306 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd80	CD80 antigen	23	98	2	30

Sequence references in MGI

J:13179 Selvakumar A, et al., Genomic organization of the mouse B-lymphocyte activation antigen B7. Immunogenetics. 1993;38(4):292-5
J:15838 Freeman GJ, et al., Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7. J Exp Med. 1991 Sep 1;174(3):625-31
J:17715 Inobe M, et al., Identification of an alternatively spliced form of the murine homologue of B7. Biochem Biophys Res Commun. 1994 Apr 15;200(1):443-9
J:122221 Tseng SY, et al., CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapse. J Immunol. 2005 Dec 15;175(12):7829-36
J:188462 Good-Jacobson KL, et al., CD80 expression on B cells regulates murine T follicular helper development, germinal center B cell survival, and plasma cell generation. J Immunol. 2012 May 1;188(9):4217-25