Sequence Detail

ID/Version

Q02053 P31253 A6H6S6 Q542H8 (UniProt | EBI)

Last sequence update: 1993-04-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Ubiquitin-like modifier-activating enzyme 1; EC=6.2.1.45 {ECO:0000250|UniProtKB:P22314};AltName: Full=Ubiquitin-activating enzyme E1;AltName: Full=Ubiquitin-activating enzyme E1 X;AltName: Full=Ubiquitin-like modifier-activating enzy

Provider

SWISS-PROT

Sequence

Polypeptide 1058 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Uba1	ubiquitin-like modifier activating enzyme 1	35	105	3	10

Sequence references in MGI

J:2259 Imai N, et al., Cloning and sequence of a functionally active cDNA encoding the mouse ubiquitin-activating enzyme E1. Gene. 1992 Sep 10;118(2):279-82
J:2972 Mitchell MJ, et al., Homology of a candidate spermatogenic gene from the mouse Y chromosome to the ubiquitin-activating enzyme E1. Nature. 1991 Dec 12;354(6353):483-6
J:24151 Chang BH, et al., Estimating the intensity of male-driven evolution in rodents by using X-linked and Y-linked Ube 1 genes and pseudogenes. J Mol Evol. 1995 Jan;40(1):70-7
J:36991 Odorisio T, et al., Transcriptional analysis of the candidate spermatogenesis gene Ube1y and of the closely related Ube1x shows that they are coexpressed in spermatogonia and spermatids but are repressed in pachytene spermatocytes. Dev Biol. 1996 Nov 25;180(1):336-43
J:46848 Caubin J, et al., Isolation of genomic DNA fragments corresponding to genes modulated in vivo by a transcription factor. Nucleic Acids Res. 1994 Oct 11;22(20):4132-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100999 Giannakopoulos NV, et al., Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. Biochem Biophys Res Commun. 2005 Oct 21;336(2):496-506
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89