Sequence Detail

ID/Version

Q02085 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Zinc finger protein SNAI1;AltName: Full=Protein snail homolog 1; Short=Protein sna;

Provider

SWISS-PROT

Sequence

Polypeptide 264 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Snai1	snail family zinc finger 1	68	165	4	15

Sequence references in MGI

J:3088 Nieto MA, et al., Cloning and developmental expression of Sna, a murine homologue of the Drosophila snail gene. Development. 1992 Sep;116(1):227-37
J:3684 Smith DE, et al., Isolation of Sna, a mouse gene homologous to the Drosophila genes snail and escargot: its expression pattern suggests multiple roles during postimplantation development [published erratum appears in Development 1993 Mar;117(3):preceding table of contents]. Development. 1992 Dec;116(4):1033-9
J:42380 Jiang R, et al., Genomic organization and chromosomal localization of the mouse snail (Sna) gene. Mamm Genome. 1997 Sep;8(9):686-8
J:60189 Cano A, et al., The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol. 2000 Feb;2(2):76-83
J:72861 Carver EA, et al., The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol Cell Biol. 2001 Dec;21(23):8184-8
J:84387 Dominguez D, et al., Phosphorylation regulates the subcellular location and activity of the snail transcriptional repressor. Mol Cell Biol. 2003 Jul;23(14):5078-89
J:183217 Langer EM, et al., Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus. Dev Cell. 2008 Mar;14(3):424-36
J:184115 Rodriguez MI, et al., Poly(ADP-ribose)-dependent regulation of Snail1 protein stability. Oncogene. 2011 Oct 20;30(42):4365-72
J:206163 Millanes-Romero A, et al., Regulation of heterochromatin transcription by Snail1/LOXL2 during epithelial-to-mesenchymal transition. Mol Cell. 2013 Dec 12;52(5):746-57