Sequence Detail

ID/Version

Q04750 A2A4B7 (UniProt | EBI)

Last sequence update: 2007-07-24
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=DNA topoisomerase 1; EC=5.6.2.1 {ECO:0000255|PROSITE-ProRule:PRU10130};AltName: Full=DNA topoisomerase I;

Provider

SWISS-PROT

Sequence

Polypeptide 767 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Top1	topoisomerase (DNA) I	59	100	4	290

Sequence references in MGI

J:4311 Koiwai O, et al., Cloning of the mouse cDNA encoding DNA topoisomerase I and chromosomal location of the gene. Gene. 1993 Mar 30;125(2):211-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89