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Sequence Detail
ID/Version
Q04750 A2A4B7 (UniProt | EBI) Last sequence update: 2007-07-24
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=DNA topoisomerase 1; EC=5.6.2.1 {ECO:0000255|PROSITE-ProRule:PRU10130};AltName: Full=DNA topoisomerase I;
Provider SWISS-PROT
Sequence
Polypeptide 767 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Top1 topoisomerase (DNA) I 58 100 4 290
Sequence references in MGI J:4311 Koiwai O, et al., Cloning of the mouse cDNA encoding DNA topoisomerase I and chromosomal location of the gene. Gene. 1993 Mar 30;125(2):211-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory