ID/Version |
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Sequence description from provider |
RecName: Full=Sex-determining region Y protein {ECO:0000303|PubMed:1518820};AltName: Full=Testis-determining factor {ECO:0000250|UniProtKB:Q05066}; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
392
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:2258
Gubbay J, et al., Inverted repeat structure of the Sry locus in mice. Proc Natl Acad Sci U S A. 1992 Sep 1;89(17):7953-7
J:10645 Gubbay J, et al., A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes [see comments]. Nature. 1990 Jul 19;346(6281):245-50 J:17098 Coward P, et al., Polymorphism of a CAG trinucleotide repeat within Sry correlates with B6.YDom sex reversal. Nat Genet. 1994 Mar;6(3):245-50 J:18226 Giese K, et al., Distinct DNA-binding properties of the high mobility group domain of murine and human SRY sex-determining factors. Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3368-72 J:26101 Hacker A, et al., Expression of Sry, the mouse sex determining gene. Development. 1995 Jun;121(6):1603-14 J:27741 Jeske YW, et al., Expression of a linear Sry transcript in the mouse genital ridge. Nat Genet. 1995 Aug;10(4):480-2 J:49298 Tucker PK, et al., Rapid evolution of the sex determining locus in Old World mice and rats. Nature. 1993 Aug 19;364(6439):715-7 J:73280 Albrecht KH, et al., Evidence that sry is expressed in pre-sertoli cells and sertoli and granulosa cells have a common precursor. Dev Biol. 2001 Dec 1;240(1):92-107 J:74052 Mayer A, et al., Developmental profile of Sry transcripts in mouse brain. Neurogenetics. 2000 Sep;3(1):25-30 J:103823 Thevenet L, et al., NHERF2/SIP-1 interacts with mouse SRY via a different mechanism than human SRY. J Biol Chem. 2005 Nov 18;280(46):38625-30 J:123875 Dewing P, et al., Direct regulation of adult brain function by the male-specific factor SRY. Curr Biol. 2006 Feb 21;16(4):415-20 J:164348 Oh HJ, et al., Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein. Biol Reprod. 2005 Feb;72(2):407-15 J:297093 Miyawaki S, et al., The mouse Sry locus harbors a cryptic exon that is essential for male sex determination. Science. 2020 Oct 2;370(6512):121-124 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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