Sequence Detail

ID/Version

Q059U7 Q8BS60 Q8C9Y0 Q80TG0 (UniProt | EBI)

Last sequence update: 2006-11-14
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Protein inturned;AltName: Full=Inturned planar cell polarity effector homolog;AltName: Full=PDZ domain-containing protein 6;

Provider

SWISS-PROT

Sequence

Polypeptide 942 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Intu	inturned planar cell polarity protein	43	97	3	7

Sequence references in MGI

J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:159120 Zeng H, et al., PCP effector gene Inturned is an important regulator of cilia formation and embryonic development in mammals. Dev Biol. 2010 Mar 15;339(2):418-28
J:174196 Heydeck W, et al., PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube. Dev Dyn. 2011 Aug;240(8):1938-48
J:243791 Toriyama M, et al., The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery. Nat Genet. 2016 Jun;48(6):648-56
J:255486 Agbu SO, et al., The small GTPase RSG1 controls a final step in primary cilia initiation. J Cell Biol. 2018 Jan 2;217(1):413-427
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:352395 Langousis G, et al., Structure of the ciliogenesis-associated CPLANE complex. Sci Adv. 2022 Apr 15;8(15):eabn0832