Sequence Detail

ID/Version

Q06806 Q811F4 Q8BGI2 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Tyrosine-protein kinase receptor Tie-1; EC=2.7.10.1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1134 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	52	139	3	23

Sequence references in MGI

J:14345 Iwama A, et al., Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells. Biochem Biophys Res Commun. 1993 Aug 31;195(1):301-9
J:15180 Sato TN, et al., Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system [published erratum appears in Proc Natl Acad Sci U S A 1993 Dec 15;90(24):12056]. Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9355-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:123058 Korhonen J, et al., Endothelial-specific gene expression directed by the tie gene promoter in vivo. Blood. 1995 Sep 1;86(5):1828-35
J:193673 Korhonen J, et al., Enhanced expression of the tie receptor tyrosine kinase in endothelial cells during neovascularization. Blood. 1992 Nov 15;80(10):2548-55
J:262023 Morooka N, et al., Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89