Sequence Detail

ID/Version

Q09143 P30824 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=High affinity cationic amino acid transporter 1; Short=CAT-1 {ECO:0000250|UniProtKB:P30825}; Short=CAT1;AltName: Full=Ecotropic retroviral leukemia receptor;AltName: Full=Ecotropic retrovirus receptor {ECO:0000303|PubMed:1652

Provider

SWISS-PROT

Sequence

Polypeptide 622 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc7a1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	44	101	4	79

Sequence references in MGI

J:9786 Albritton LM, et al., A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell. 1989 May 19;57(4):659-66
J:11385 Kim JW, et al., Transport of cationic amino acids by the mouse ecotropic retrovirus receptor [see comments]. Nature. 1991 Aug 22;352(6337):725-8
J:40643 Closs EI, et al., Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. Biochemistry. 1997 May 27;36(21):6462-8
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:180208 Erez A, et al., Requirement of argininosuccinate lyase for systemic nitric oxide production. Nat Med. 2011 Dec;17(12):1619-26
J:222036 Hlynialuk CJ, et al., The Mitochondrial Metallochaperone SCO1 Is Required to Sustain Expression of the High-Affinity Copper Transporter CTR1 and Preserve Copper Homeostasis. Cell Rep. 2015 Feb 12;
J:252376 Baker ZN, et al., The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart. Hum Mol Genet. 2017 Dec 1;26(23):4617-4628
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:326243 Wang H, et al., Cell-surface receptor for ecotropic murine retroviruses is a basic amino-acid transporter. Nature. 1991 Aug 22;352(6337):729-31