Sequence Detail

ID/Version

Q149L7 Q9Z151 Q3TQA9 M0QWH9 Q9CVZ9 A0A087WPL6 (UniProt | EBI)

Last sequence update: 2018-12-05
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Cytotoxic and regulatory T-cell molecule;AltName: Full=Class-I MHC-restricted T-cell-associated molecule;AltName: CD_antigen=CD355;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 393 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Crtam	cytotoxic and regulatory T cell molecule	41	96	2	7

Sequence references in MGI

J:62065 Kennedy J, et al., A molecular analysis of NKT cells: identification of a class-I restricted T cell-associated molecule (CRTAM). J Leukoc Biol. 2000 May;67(5):725-34
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114711 Boles KS, et al., The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM. Blood. 2005 Aug 1;106(3):779-86
J:145314 Yeh JH, et al., Regulation of a late phase of T cell polarity and effector functions by Crtam. Cell. 2008 Mar 7;132(5):846-59
J:152770 Takeuchi A, et al., CRTAM confers late-stage activation of CD8+ T cells to regulate retention within lymph node. J Immunol. 2009 Oct 1;183(7):4220-8
J:212409 Cortez VS, et al., CRTAM controls residency of gut CD4+CD8+ T cells in the steady state and maintenance of gut CD4+ Th17 during parasitic infection. J Exp Med. 2014 Apr 7;211(4):623-33