Sequence Detail

ID/Version

Q3TH73 Q3U8L3 Q6P9J3 Q920A8 Q3U103 (UniProt | EBI)

Last sequence update: 2005-10-11
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Protein tweety homolog 2; Short=mTTY2;AltName: Full=Volume-regulated anion channel subunit Ttyh2 {ECO:0000303|PubMed:31138989};

Provider

SWISS-PROT

Sequence

Polypeptide 532 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ttyh2	tweety family member 2	14	99	4	11

Sequence references in MGI

J:72230 Rae FK, et al., TTYH2, a Human Homologue of the Drosophila melanogaster Gene tweety, Is Located on 17q24 and Upregulated in Renal Cell Carcinoma. Genomics. 2001 Oct;77(3):200-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:345046 Han YE, et al., Tweety-homolog (Ttyh) Family Encodes the Pore-forming Subunits of the Swelling-dependent Volume-regulated Anion Channel (VRAC(swell)) in the Brain. Exp Neurobiol. 2019 Apr;28(2):183-215
J:345049 Li B, et al., Structures of tweety homolog proteins TTYH2 and TTYH3 reveal a Ca(2+)-dependent switch from intra- to intermembrane dimerization. Nat Commun. 2021 Nov 25;12(1):6913