Sequence Detail

ID/Version

Q3TXX3 Q8CFP8 (UniProt | EBI)

Last sequence update: 2006-07-11
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Protrudin;AltName: Full=Zinc finger FYVE domain-containing protein 27;

Provider

SWISS-PROT

Sequence

Polypeptide 415 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Zfyve27	zinc finger, FYVE domain containing 27	73	98	3	9

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114677 Shirane M, et al., Protrudin induces neurite formation by directional membrane trafficking. Science. 2006 Nov 3;314(5800):818-21
J:132961 Shirane M, et al., Regulation of apoptosis and neurite extension by FKBP38 is required for neural tube formation in the mouse. Genes Cells. 2008 Jun;13(6):635-51
J:214135 Hashimoto Y, et al., Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia. J Biol Chem. 2014 May 9;289(19):12946-61
J:215725 Ohnishi T, et al., Identification and characterization of a neuron-specific isoform of protrudin. Genes Cells. 2014 Feb;19(2):97-111
J:235257 Matsuzaki F, et al., Protrudin serves as an adaptor molecule that connects KIF5 and its cargoes in vesicular transport during process formation. Mol Biol Cell. 2011 Dec;22(23):4602-20