Sequence Detail

ID/Version

Q3UHD1 Q3UH36 Q8CGM0 (UniProt | EBI)

Last sequence update: 2005-10-11
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Adhesion G protein-coupled receptor B1 {ECO:0000312|MGI:MGI:1933736};AltName: Full=Brain-specific angiogenesis inhibitor 1 {ECO:0000303|PubMed:11245925};Contains: RecName: Full=Vasculostatin-120 {ECO:0000250|UniProtKB:O14514}; Sho

Provider

SWISS-PROT

Sequence

Polypeptide 1582 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Adgrb1	adhesion G protein-coupled receptor B1	54	102	4	22

Sequence references in MGI

J:68103 Koh JT, et al., Characterization of mouse brain-specific angiogenesis inhibitor 1 (BAI1) and phytanoyl-CoA alpha-hydroxylase-associated protein 1, a novel BAI1-binding protein. Brain Res Mol Brain Res. 2001 Mar 5;87(2):223-37
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:127717 Park D, et al., BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module. Nature. 2007 Nov 15;450(7168):430-4
J:169123 Das S, et al., Brain angiogenesis inhibitor 1 (BAI1) is a pattern recognition receptor that mediates macrophage binding and engulfment of Gram-negative bacteria. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2136-41
J:196966 Duman JG, et al., The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites. J Neurosci. 2013 Apr 17;33(16):6964-78
J:198690 Hochreiter-Hufford AE, et al., Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion. Nature. 2013 May 9;497(7448):263-7
J:202713 Stephenson JR, et al., Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density. J Biol Chem. 2013 Aug 2;288(31):22248-56
J:222100 Zhu D, et al., BAI1 regulates spatial learning and synaptic plasticity in the hippocampus. J Clin Invest. 2015 Apr;125(4):1497-508
J:243397 Sokolowski JD, et al., Brain-specific angiogenesis inhibitor-1 expression in astrocytes and neurons: implications for its dual function as an apoptotic engulfment receptor. Brain Behav Immun. 2011 Jul;25(5):915-21
J:243461 Billings EA, et al., The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria. Sci Signal. 2016 Feb 02;9(413):ra14
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89