Sequence Detail

ID/Version

Q3UIK4 Q6ZPL2 Q80UR9 (UniProt | EBI)

Last sequence update: 2005-10-11
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=N(6)-adenosine-methyltransferase non-catalytic subunit METTL14;AltName: Full=Methyltransferase-like protein 14;

Provider

SWISS-PROT

Sequence

Polypeptide 456 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mettl14	methyltransferase 14, N6-adenosine-methyltransferase subunit	43	111	3	28

Sequence references in MGI

J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:207885 Wang Y, et al., N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells. Nat Cell Biol. 2014 Feb;16(2):191-8
J:247703 Yoon KJ, et al., Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation. Cell. 2017 Nov 02;171(4):877-889.e17
J:250428 Lin Z, et al., Mettl3-/Mettl14-mediated mRNA N(6)-methyladenosine modulates murine spermatogenesis. Cell Res. 2017 Oct;27(10):1216-1230
J:261823 Wen J, et al., Zc3h13 Regulates Nuclear RNA m(6)A Methylation and Mouse Embryonic Stem Cell Self-Renewal. Mol Cell. 2018 Mar 15;69(6):1028-1038.e6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:345540 Knuckles P, et al., Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m(6)A machinery component Wtap/Fl(2)d. Genes Dev. 2018 Mar 1;32(5-6):415-429