Sequence Detail

ID/Version

Q3UN02 (UniProt | EBI)

Last sequence update: 2007-06-26
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Lysocardiolipin acyltransferase 1; EC=2.3.1.- {ECO:0000269|PubMed:15152008};AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 8 {ECO:0000250|UniProtKB:Q6UWP7}; Short=1-AGP acyltransferase 8; Short=1-AGPAT 8;

Provider

SWISS-PROT

Sequence

Polypeptide 376 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lclat1	lysocardiolipin acyltransferase 1	14	100	3	20

Sequence references in MGI

J:91904 Cao J, et al., A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated Acyl-CoA:lysocardiolipin acyltransferase (ALCAT1) in mouse. J Biol Chem. 2004 Jul 23;279(30):31727-34
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:111940 Agarwal AK, et al., Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: cloning, tissue distribution, gene structure, and enzymatic activity. Arch Biochem Biophys. 2006 May 15;449(1-2):64-76
J:149116 Wang C, et al., Mouse lysocardiolipin acyltransferase controls the development of hematopoietic and endothelial lineages during in vitro embryonic stem-cell differentiation. Blood. 2007 Nov 15;110(10):3601-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89