Sequence Detail

ID/Version

Q3UU41 B2RVG2 Q5SX69 (UniProt | EBI)

Last sequence update: 2005-10-11
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=SLP adapter and CSK-interacting membrane protein;

Provider

SWISS-PROT

Sequence

Polypeptide 150 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Scimp	SLP adaptor and CSK interacting membrane protein	34	96	2	6

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:178776 Draber P, et al., SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling. Mol Cell Biol. 2011 Nov;31(22):4550-62
J:235794 Kralova J, et al., The Transmembrane Adaptor Protein SCIMP Facilitates Sustained Dectin-1 Signaling in Dendritic Cells. J Biol Chem. 2016 Aug 5;291(32):16530-40
J:244275 Luo L, et al., SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages. Nat Commun. 2017 Jan 18;8:14133
J:276512 Luo L, et al., Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP. Immunol Cell Biol. 2017 Jul;95(6):564-570
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89