Sequence Detail

ID/Version

Q3UZD5 Q2I2X1 Q2I2X0 Q3UX75 B9EIB0 (UniProt | EBI)

Last sequence update: 2005-10-11
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Putative histone-lysine N-methyltransferase PRDM6; EC=2.1.1.361 {ECO:0000305|PubMed:17662997};AltName: Full=PR domain zinc finger protein 6;AltName: Full=PR domain-containing protein 6;AltName: Full=PR domain-containing protein in sm

Provider

SWISS-PROT

Sequence

Polypeptide 596 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prdm6	PR domain containing 6	16	105	3	5

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106935 Davis CA, et al., PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells. Mol Cell Biol. 2006 Apr;26(7):2626-36
J:130641 Wu Y, et al., PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation. J Mol Cell Cardiol. 2008 Jan;44(1):47-58
J:252161 Li N, et al., Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus. Am J Hum Genet. 2016 Jun 2;98(6):1082-1091