Sequence Detail

ID/Version

Q4KL25 B2KF30 (UniProt | EBI)

Last sequence update: 2005-08-02
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=LHFPL tetraspan subfamily member 5 protein {ECO:0000250|UniProtKB:Q8TAF8};AltName: Full=Lipoma HMGIC fusion partner-like 5 protein {ECO:0000312|MGI:MGI:1915382};AltName: Full=Tetraspan membrane protein of hair cell stereocilia {ECO:0000303|P

Provider

SWISS-PROT

Sequence

Polypeptide 219 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lhfpl5	lipoma HMGIC fusion partner-like 5	15	105	4	25

Sequence references in MGI

J:98396 Longo-Guess CM, et al., A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice. Proc Natl Acad Sci U S A. 2005 May 31;102(22):7894-9
J:193334 Xiong W, et al., TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells. Cell. 2012 Dec 7;151(6):1283-95
J:217448 Zhao B, et al., TMIE is an essential component of the mechanotransduction machinery of cochlear hair cells. Neuron. 2014 Dec 3;84(5):954-67
J:241136 Zhao F, et al., Novel function of LHFPL2 in female and male distal reproductive tract development. Sci Rep. 2016 Mar 11;6:23037
J:249939 Cunningham CL, et al., The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells. Elife. 2017 May 15;6:e24318
J:344636 Fettiplace R, et al., The conductance and organization of the TMC1-containing mechanotransducer channel complex in auditory hair cells. Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2210849119