Sequence Detail

ID/Version

Q4ZJM7 B9EKG7 Q3TYP6 (UniProt | EBI)

Last sequence update: 2008-04-29
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Otolin-1 {ECO:0000305};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 482 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Otol1	otolin 1	11	114	4	7

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:122533 Zhao X, et al., Gene targeting reveals the role of Oc90 as the essential organizer of the otoconial organic matrix. Dev Biol. 2007 Apr 15;304(2):508-24
J:240919 Yang H, et al., Matrix recruitment and calcium sequestration for spatial specific otoconia development. PLoS One. 2011;6(5):e20498
J:263439 Deans MR, et al., Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1. PLoS One. 2010 Sep 15;5(9):e12765
J:263462 Moreland KT, et al., In vitro calcite crystal morphology is modulated by otoconial proteins otolin-1 and otoconin-90. PLoS One. 2014;9(4):e95333
J:263486 Holubowicz R, et al., Effect of calcium ions on structure and stability of the C1q-like domain of otolin-1 from human and zebrafish. FEBS J. 2017 Dec;284(24):4278-4297