ID/Version |
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Sequence description from provider |
RecName: Full=Sodium/hydrogen exchanger 9B2;AltName: Full=NHA-oc {ECO:0000303|PubMed:17988971};AltName: Full=Na(+)/H(+) exchanger NHA2;AltName: Full=Na(+)/H(+) exchanger-like domain-containing protein 2; Short=NHE domain-containing protein 2;AltNa | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
547
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:99680
The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:134223 Lee SH, et al., NHE10, a novel osteoclast-specific member of the Na+/H+ exchanger family, regulates osteoclast differentiation and survival. Biochem Biophys Res Commun. 2008 May 2;369(2):320-6 J:162142 Hofstetter W, et al., Sodium/hydrogen exchanger NHA2 in osteoclasts: subcellular localization and role in vitro and in vivo. Bone. 2010 Aug;47(2):331-40 J:193573 Charles JF, et al., The collection of NFATc1-dependent transcripts in the osteoclast includes numerous genes non-essential to physiologic bone resorption. Bone. 2012 Nov;51(5):902-12 J:197386 Deisl C, et al., Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in beta-cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):10004-9 J:240371 Chen SR, et al., Sodium-hydrogen exchanger NHA1 and NHA2 control sperm motility and male fertility. Cell Death Dis. 2016 Mar 24;7:e2152 J:333977 Kondapalli KC, et al., NHA2 is expressed in distal nephron and regulated by dietary sodium. J Physiol Biochem. 2017 May;73(2):199-205 J:334240 Anderegg MA, et al., The sodium/proton exchanger NHA2 regulates blood pressure through a WNK4-NCC dependent pathway in the kidney. Kidney Int. 2021 Feb;99(2):350-363 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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