Sequence Detail

ID/Version

Q5BN45 (UniProt | EBI)

Last sequence update: 2005-04-12
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Piercer of microtubule wall 1 protein {ECO:0000312|MGI:MGI:1916577}; Short=Pierce1 {ECO:0000305};AltName: Full=p53-induced expression in RB-null cells protein 1 {ECO:0000303|PubMed:21159655};

Provider

SWISS-PROT

Sequence

Polypeptide 167 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pierce1	piercer of microtubule wall 1	25	101	3	11

Sequence references in MGI

J:167598 Sung YH, et al., Pierce1, a novel p53 target gene contributing to the ultraviolet-induced DNA damage response. Cancer Res. 2010 Dec 15;70(24):10454-63
J:252050 Sung YH, et al., PIERCE1 is critical for specification of left-right asymmetry in mice. Sci Rep. 2016 Jun 16;6:27932
J:316131 Gui M, et al., De novo identification of mammalian ciliary motility proteins using cryo-EM. Cell. 2021 Nov 11;184(23):5791-5806.e19
J:338030 Zhou L, et al., Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19
J:342625 Chen Z, et al., De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. Cell. 2023 Nov 9;186(23):5041-5053.e19
J:352387 Tai L, et al., In-cell structural insight into the stability of sperm microtubule doublet. Cell Discov. 2023 Nov 21;9(1):116