Sequence Detail

ID/Version

Q5FWI2 Q80T66 (UniProt | EBI)

Last sequence update: 2005-03-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Secretin receptor {ECO:0000303|PubMed:30449620}; Short=SCT-R;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 447 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sctr	secretin receptor	23	96	2	8

Sequence references in MGI

J:83410 Vassilatis DK, et al., The G protein-coupled receptor repertoires of human and mouse. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4903-8
J:114853 Nishijima I, et al., Secretin receptor-deficient mice exhibit impaired synaptic plasticity and social behavior. Hum Mol Genet. 2006 Nov 1;15(21):3241-50
J:121376 Chu JY, et al., Phenotypes developed in secretin receptor-null mice indicated a role for secretin in regulating renal water reabsorption. Mol Cell Biol. 2007 Apr;27(7):2499-511
J:208291 Sekar R, et al., Lipolytic actions of secretin in mouse adipocytes. J Lipid Res. 2014 Feb;55(2):190-200
J:216627 Sekar R, et al., Secretin receptor-knockout mice are resistant to high-fat diet-induced obesity and exhibit impaired intestinal lipid absorption. FASEB J. 2014 Aug;28(8):3494-505
J:273530 Cheng CY, et al., Central and peripheral administration of secretin inhibits food intake in mice through the activation of the melanocortin system. Neuropsychopharmacology. 2011 Jan;36(2):459-71
J:281249 Li Y, et al., Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation. Cell. 2018 Nov 8;