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Sequence Detail
ID/Version
Q5MJS3 Q6PKA8 Q4FJP0 Q8JZP7 Q571A3 (UniProt | EBI) Last sequence update: 2005-02-01
Last annotation update: 2024-11-27
Sequence
description
from provider
RecName: Full=Extracellular serine/threonine protein kinase FAM20C {ECO:0000305}; EC=2.7.11.1 {ECO:0000269|PubMed:22900076};AltName: Full=Dentin matrix protein 4 {ECO:0000303|PubMed:17369251}; Short=DMP-4 {ECO:0000303|PubMed:17369251};AltN
Provider SWISS-PROT
Sequence
Polypeptide 579 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Fam20c FAM20C, golgi associated secretory pathway kinase 59 101 4 6
Sequence references in MGI J:122675 Hao J, et al., Dentin matrix protein 4, a novel secretory calcium-binding protein that modulates odontoblast differentiation. J Biol Chem. 2007 May 25;282(21):15357-65
J:186384 Vogel P, et al., Amelogenesis imperfecta and other biomineralization defects in Fam20a and Fam20c null mice. Vet Pathol. 2012 Nov;49(6):998-1017
J:211241 O'Sullivan J, et al., Whole-Exome sequencing identifies FAM20A mutations as a cause of amelogenesis imperfecta and gingival hyperplasia syndrome. Am J Hum Genet. 2011 May 13;88(5):616-20
J:222145 Ishikawa HO, et al., The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins. PLoS One. 2012;7(8):e42988
J:222164 Cui J, et al., A secretory kinase complex regulates extracellular protein phosphorylation. Elife. 2015;4:e06120

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory