Sequence Detail

ID/Version

Q5NCQ5 Q8R445 Q80UX6 (UniProt | EBI)

Last sequence update: 2005-02-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305}; EC=2.5.1.108 {ECO:0000305|PubMed:15485916};AltName: Full=Diphthamide biosynthesis protein 1;AltName: Full=Diphtheria toxin resistance protein 1 {ECO:0000305};AltN

Provider

SWISS-PROT

Sequence

Polypeptide 438 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dph1	diphthamide biosynthesis 1	18	101	3	19

Sequence references in MGI

J:71516 Chen CM, et al., Cloning, structure, and expression of the mouse Ovca1 gene. Biochem Biophys Res Commun. 2001 Sep 7;286(5):1019-26
J:88090 Chen CM, et al., Ovca1 regulates cell proliferation, embryonic development, and tumorigenesis. Genes Dev. 2004 Feb 1;18(3):320-32
J:95659 Chen CM, et al., OVCA1: tumor suppressor gene. Curr Opin Genet Dev. 2005 Feb;15(1):49-54
J:131468 Liu S, et al., Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. Mol Cell Biol. 2004 Nov;24(21):9487-97
J:214744 Yu YR, et al., Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome. Hum Mol Genet. 2014 Nov 1;23(21):5579-96
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89