Sequence Detail

ID/Version

Q5QD14 (UniProt | EBI)

Last sequence update: 2005-01-04
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Trace amine-associated receptor 5 {ECO:0000303|PubMed:15718104}; Short=TaR-5; Short=Trace amine receptor 5 {ECO:0000303|PubMed:15718104}; Short=mTaar5 {ECO:0000303|PubMed:15718104};AltName: Full=Trimethylamine recepto

Provider

SWISS-PROT

Sequence

Polypeptide 337 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Taar5	trace amine-associated receptor 5	18	99	7	12

Sequence references in MGI

J:95733 Lindemann L, et al., Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors. Genomics. 2005 Mar;85(3):372-85
J:111708 Liberles SD, et al., A second class of chemosensory receptors in the olfactory epithelium. Nature. 2006 Aug 10;442(7103):645-50
J:188715 Johnson MA, et al., Neurons expressing trace amine-associated receptors project to discrete glomeruli and constitute an olfactory subsystem. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13410-5
J:197486 Li Q, et al., Synchronous evolution of an odor biosynthesis pathway and behavioral response. Curr Biol. 2013 Jan 7;23(1):11-20
J:197678 Dewan A, et al., Non-redundant coding of aversive odours in the main olfactory pathway. Nature. 2013 May 23;497(7450):486-9
J:236048 Saraiva LR, et al., Combinatorial effects of odorants on mouse behavior. Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):E3300-6
J:265894 Dewan A, et al., Single olfactory receptors set odor detection thresholds. Nat Commun. 2018 Jul 23;9(1):2887
J:287282 Espinoza S, et al., Trace Amine-Associated Receptor 5 Provides Olfactory Input Into Limbic Brain Areas and Modulates Emotional Behaviors and Serotonin Transmission. Front Mol Neurosci. 2020;13:18
J:315190 Kalinina DS, et al., Role of the trace amine associated receptor 5 (TAAR5) in the sensorimotor functions. Sci Rep. 2021 Nov 29;11(1):23092
J:327988 Maggi S, et al., Improved cognitive performance in trace amine-associated receptor 5 (TAAR5) knock-out mice. Sci Rep. 2022 Aug 29;12(1):14708
J:352390 Guo L, et al., Structural basis of amine odorant perception by a mammal olfactory receptor. Nature. 2023 Jun;618(7963):193-200
J:352398 Ferrero DM, et al., Agonists for 13 trace amine-associated receptors provide insight into the molecular basis of odor selectivity. ACS Chem Biol. 2012 Jul 20;7(7):1184-9