Sequence Detail

ID/Version

Q5SZ99 B9EKD3 (UniProt | EBI)

Last sequence update: 2004-12-21
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase TRIM38 {ECO:0000305}; EC=2.3.2.27 {ECO:0000269|PubMed:22539786, ECO:0000269|PubMed:26392463};AltName: Full=E3 SUMO-protein ligase TRIM38 {ECO:0000305}; EC=2.3.2.- {ECO:0000269|PubMed:27637147};AltN

Provider

SWISS-PROT

Sequence

Polypeptide 471 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Trim38	tripartite motif-containing 38	30	96	7	10

Sequence references in MGI

J:188742 Zhao W, et al., Tripartite motif-containing protein 38 negatively regulates TLR3/4- and RIG-I-mediated IFN-beta production and antiviral response by targeting NAP1. J Immunol. 2012 Jun 1;188(11):5311-8
J:239773 Hu MM, et al., TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms. J Immunol. 2015 Nov 01;195(9):4415-25
J:259271 Hu MM, et al., Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus. Immunity. 2016 Sep 20;45(3):555-569