Sequence Detail

ID/Version

Q5U4H9 Q3UI10 Q3UJ63 Q3UKL9 Q3UJ26 Q9WV42 (UniProt | EBI)

Last sequence update: 2004-12-07
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Nuclear receptor coactivator 4 {ECO:0000312|MGI:MGI:1350932}; Short=NCoA-4 {ECO:0000305};AltName: Full=Androgen receptor coactivator protein {ECO:0000305};AltName: Full=Ferritin cargo receptor NCOA4 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 625 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ncoa4	nuclear receptor coactivator 4	5	107	3	72

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:215322 Bellelli R, et al., NCOA4 transcriptional coactivator inhibits activation of DNA replication origins. Mol Cell. 2014 Jul 3;55(1):123-37
J:217701 Dowdle WE, et al., Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol. 2014 Nov;16(11):1069-79
J:315955 Bellelli R, et al., NCOA4 Deficiency Impairs Systemic Iron Homeostasis. Cell Rep. 2016 Jan 26;14(3):411-421