Sequence Detail

ID/Version

Q5XJY4 Q641T5 Q3U9T5 (UniProt | EBI)

Last sequence update: 2004-11-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Presenilin-associated rhomboid-like protein, mitochondrial; EC=3.4.21.105 {ECO:0000250|UniProtKB:Q9H300};AltName: Full=Mitochondrial intramembrane-cleaving protease PARL;Contains: RecName: Full=P-beta; Short=Pbeta;Flags: P

Provider

SWISS-PROT

Sequence

Polypeptide 377 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Parl	presenilin associated, rhomboid-like	29	96	3	14

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116017 Cipolat S, et al., Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling. Cell. 2006 Jul 14;126(1):163-75
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89