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Sequence Detail
ID/Version
Q5XJY4 Q641T5 Q3U9T5 (UniProt | EBI) Last sequence update: 2004-11-23
Last annotation update: 2024-11-27
Sequence
description
from provider
RecName: Full=Presenilin-associated rhomboid-like protein, mitochondrial; EC=3.4.21.105 {ECO:0000250|UniProtKB:Q9H300};AltName: Full=Mitochondrial intramembrane-cleaving protease PARL;Contains: RecName: Full=P-beta; Short=Pbeta;Flags: P
Provider SWISS-PROT
Sequence
Polypeptide 377 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Parl presenilin associated, rhomboid-like 29 96 3 14
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116017 Cipolat S, et al., Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling. Cell. 2006 Jul 14;126(1):163-75
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory