Sequence Detail

ID/Version

Q5XPT3 Q5XPT2 Q8BJZ8 Q8K253 A2AHG9 (UniProt | EBI)

Last sequence update: 2004-11-23
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Xylosyl- and glucuronyltransferase LARGE2 {ECO:0000305}; EC=2.4.-.- {ECO:0000269|PubMed:23125099, ECO:0000269|PubMed:23135544};AltName: Full=Glycosyltransferase-like 1B;AltName: Full=LARGE xylosyl- and glucuronyltransferase 2 {ECO:00

Provider

SWISS-PROT

Sequence

Polypeptide 690 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Large2	LARGE xylosyl- and glucuronyltransferase 2	14	99	3	9

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:215859 Ashikov A, et al., LARGE2 generates the same xylose- and glucuronic acid-containing glycan structures as LARGE. Glycobiology. 2013 Mar;23(3):303-9
J:215860 Inamori K, et al., Xylosyl- and glucuronyltransferase functions of LARGE in alpha-dystroglycan modification are conserved in LARGE2. Glycobiology. 2013 Mar;23(3):295-302
J:217071 Inamori K, et al., Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of alpha-dystroglycan in cells and tissues. J Biol Chem. 2014 Oct 10;289(41):28138-48
J:348635 Inamori KI, et al., LARGE2-dependent glycosylation confers laminin-binding ability on proteoglycans. Glycobiology. 2016 Dec;26(12):1284-1296