Sequence Detail

ID/Version

Q60722 Q60721 Q62211 Q80UE8 Q64072 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Transcription factor 4; Short=TCF-4;AltName: Full=Class A helix-loop-helix transcription factor ME2;AltName: Full=Immunoglobulin transcription factor 2; Short=ITF-2; Short=MITF-2;AltName: Full=SL3-3 enhancer factor 2;

Provider

SWISS-PROT

Sequence

Polypeptide 670 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tcf4	transcription factor 4	59	132	3	35

Sequence references in MGI

J:20051 Soosaar A, et al., Expression of basic-helix-loop-helix transcription factor ME2 during brain development and in the regions of neuronal plasticity in the adult brain. Brain Res Mol Brain Res. 1994 Aug;25(1-2):176-80
J:31425 Skerjanc IS, et al., A splice variant of the ITF-2 transcript encodes a transcription factor that inhibits MyoD activity. J Biol Chem. 1996 Feb 16;271(7):3555-61
J:38018 Pscherer A, et al., The helix-loop-helix transcription factor SEF-2 regulates the activity of a novel initiator element in the promoter of the human somatostatin receptor II gene. EMBO J. 1996 Dec 2;15(23):6680-90
J:54634 Dorflinger U, et al., Activation of somatostatin receptor II expression by transcription factors MIBP1 and SEF-2 in the murine brain. Mol Cell Biol. 1999 May;19(5):3736-47
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:134786 Ravanpay AC, et al., E protein dosage influences brain development more than family member identity. J Neurosci Res. 2008 May 15;86(7):1472-81
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89