Sequence Detail

ID/Version

Q60963 Q921T4 Q8BKM3 (UniProt | EBI)

Last sequence update: 2010-11-02
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Platelet-activating factor acetylhydrolase; Short=PAF acetylhydrolase; EC=3.1.1.47 {ECO:0000269|PubMed:10066756, ECO:0000269|PubMed:18434304};AltName: Full=1-alkyl-2-acetylglycerophosphocholine esterase;AltName: Full=2-acetyl

Provider

SWISS-PROT

Sequence

Polypeptide 440 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pla2g7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	27	103	3	8

Sequence references in MGI

J:29539 Tjoelker LW, et al., Plasma platelet-activating factor acetylhydrolase is a secreted phospholipase A2 with a catalytic triad. J Biol Chem. 1995 Oct 27;270(43):25481-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:138075 Gardner AA, et al., Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high density lipoprotein. J Biol Chem. 2008 Jun 20;283(25):17099-106
J:228564 Lu J, et al., Dual roles of endogenous platelet-activating factor acetylhydrolase in a murine model of necrotizing enterocolitis. Pediatr Res. 2010 Sep;68(3):225-30