Sequence Detail

ID/Version

Q60974 Q60812 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Nuclear receptor corepressor 1; Short=N-CoR; Short=N-CoR1;AltName: Full=Retinoid X receptor-interacting protein 13; Short=RIP13;

Provider

SWISS-PROT

Sequence

Polypeptide 2453 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ncor1	nuclear receptor co-repressor 1	116	109	3	466

Sequence references in MGI

J:23077 Seol W, et al., Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors. Mol Endocrinol. 1995 Jan;9(1):72-85
J:29044 Horlein AJ, et al., Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor [see comments]. Nature. 1995 Oct 5;377(6548):397-404
J:37082 Seol W, et al., Two receptor interacting domains in the nuclear hormone receptor corepressor RIP13/N-CoR. Mol Endocrinol. 1996 Dec;10(12):1646-55
J:46724 Zamir I, et al., Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14400-5
J:66985 Laherty CD, et al., SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. Mol Cell. 1998 Jul;2(1):33-42
J:104339 Li X, et al., Tissue-specific regulation of retinal and pituitary precursor cell proliferation. Science. 2002 Aug 16;297(5584):1180-3
J:142342 Alenghat T, et al., Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology. Nature. 2008 Dec 18;456(7224):997-1000
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:144224 Bruck N, et al., A coordinated phosphorylation cascade initiated by p38MAPK/MSK1 directs RARalpha to target promoters. EMBO J. 2009 Jan 7;28(1):34-47
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:211246 Cho Y, et al., The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors. Mol Pharmacol. 2009 Dec;76(6):1360-9
J:237500 Osipovich AB, et al., Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation. Development. 2016 Dec 15;143(24):4595-4607
J:273552 Aninye IO, et al., Circadian regulation of Tshb gene expression by Rev-Erbalpha (NR1D1) and nuclear corepressor 1 (NCOR1). J Biol Chem. 2014 Jun 13;289(24):17070-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89