Sequence Detail

ID/Version

Q60997 Q80YC6 Q9JMJ9 (UniProt | EBI)

Last sequence update: 2006-01-10
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Scavenger receptor cysteine-rich domain-containing protein DMBT1 {ECO:0000305};AltName: Full=Apactin;AltName: Full=CRP-ductin;AltName: Full=Deleted in malignant brain tumors 1 protein;AltName: Full=Glycoprotein 300; Short=gp300;AltNa

Provider

SWISS-PROT

Sequence

Polypeptide 2085 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dmbt1	deleted in malignant brain tumors 1	35	108	2	10

Sequence references in MGI

J:24488 De Lisle RC, Increased expression of sulfated gp300 and acinar tissue pathology in pancreas of CFTR(-/-) mice. Am J Physiol. 1995 Apr;268(4 Pt 1):G717-23
J:30445 De Lisle RC, et al., Expression of sulfated gp300 and changes in glycosylation during pancreatic development. J Histochem Cytochem. 1996 Jan;44(1):57-66
J:32159 Cheng H, et al., CRP-ductin: a gene expressed in intestinal crypts and in pancreatic and hepatic ducts. Anat Rec. 1996 Mar;244(3):327-43
J:42636 De Lisle RC, et al., MUCLIN expression in the cystic fibrosis transmembrane conductance regulator knockout mouse. Gastroenterology. 1997 Aug;113(2):521-32
J:60657 Matsushita F, et al., Vomeroglandin/CRP-Ductin is strongly expressed in the glands associated with the mouse vomeronasal organ: identification and characterization of mouse vomeroglandin. Biochem Biophys Res Commun. 2000 Feb 16;268(2):275-81
J:84937 Madsen J, et al., CRP-ductin, the mouse homologue of gp-340/deleted in malignant brain tumors 1 (DMBT1), binds gram-positive and gram-negative bacteria and interacts with lung surfactant protein D. Eur J Immunol. 2003 Aug;33(8):2327-36
J:93477 Takito J, et al., Conversion of ES cells to columnar epithelia by hensin and to squamous epithelia by laminin. J Cell Biol. 2004 Oct 27;166(7):1093-102
J:111694 De Lisle RC, et al., Developmental expression of a mucinlike glycoprotein (MUCLIN) in pancreas and small intestine of CF mice. Am J Physiol. 1998 Aug;275(2 Pt 1):G219-27
J:130258 Renner M, et al., DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease. Gastroenterology. 2007 Nov;133(5):1499-509
J:132597 De Lisle RC, et al., Effects of Muclin (Dmbt1) deficiency on the gastrointestinal system. Am J Physiol Gastrointest Liver Physiol. 2008 Mar;294(3):G717-27
J:150701 De Lisle RC, Characterization of the major sulfated protein of mouse pancreatic acinar cells: a high molecular weight peripheral membrane glycoprotein of zymogen granules. J Cell Biochem. 1994 Nov;56(3):385-96
J:161026 Boulatnikov I, et al., Binding of the Golgi sorting receptor muclin to pancreatic zymogens through sulfated O-linked oligosaccharides. J Biol Chem. 2004 Sep 24;279(39):40918-26
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89