Sequence Detail

ID/Version

Q61025 Q5SYG9 Q99M35 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Intraflagellar transport protein 20 homolog; Short=mIFT20;

Provider

SWISS-PROT

Sequence

Polypeptide 132 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ift20	intraflagellar transport 20	87	97	3	12

Sequence references in MGI

J:86875 Baker SA, et al., IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia. J Biol Chem. 2003 Sep 5;278(36):34211-8
J:92513 Jurczyk A, et al., Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly. J Cell Biol. 2004 Aug 30;166(5):637-43
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114585 Follit JA, et al., The intraflagellar transport protein IFT20 is associated with the Golgi complex and is required for cilia assembly. Mol Biol Cell. 2006 Sep;17(9):3781-92
J:142875 Follit JA, et al., The Golgin GMAP210/TRIP11 anchors IFT20 to the Golgi complex. PLoS Genet. 2008 Dec;4(12):e1000315
J:154656 Follit JA, et al., Characterization of mouse IFT complex B. Cell Motil Cytoskeleton. 2009 Aug;66(8):457-68
J:159553 Sironen A, et al., Expression of SPEF2 during mouse spermatogenesis and identification of IFT20 as an interacting protein. Biol Reprod. 2010 Mar;82(3):580-90
J:203423 Pampliega O, et al., Functional interaction between autophagy and ciliogenesis. Nature. 2013 Oct 10;502(7470):194-200
J:233668 Broekhuis JR, et al., Regulation of cilium length and intraflagellar transport by the RCK-kinases ICK and MOK in renal epithelial cells. PLoS One. 2014;9(9):e108470
J:242894 Lehti MS, et al., SPEF2 functions in microtubule-mediated transport in elongating spermatids to ensure proper male germ cell differentiation. Development. 2017 Jul 15;144(14):2683-2693
J:264221 Kazarian E, et al., SPAG17 Is Required for Male Germ Cell Differentiation and Fertility. Int J Mol Sci. 2018 Apr 21;19(4):1252
J:265626 Zhang Z, et al., Intraflagellar transport protein IFT20 is essential for male fertility and spermiogenesis in mice. Mol Biol Cell. 2016 Sep 28;
J:281256 Schmid FM, et al., IFT20 modulates ciliary PDGFRalpha signaling by regulating the stability of Cbl E3 ubiquitin ligases. J Cell Biol. 2018 Jan 2;217(1):151-161
J:286593 Zhang L, et al., Mouse spermatogenesis-associated protein 1 (SPATA1), an IFT20 binding partner, is an acrosomal protein. Dev Dyn. 2020 Apr;249(4):543-555
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:311093 Sorusch N, et al., SANS (USH1G) Molecularly Links the Human Usher Syndrome Protein Network to the Intraflagellar Transport Module by Direct Binding to IFT-B Proteins. Front Cell Dev Biol. 2019;7:216
J:344445 Ma Y, et al., CCDC146 is required for sperm flagellum biogenesis and male fertility in mice. Cell Mol Life Sci. 2023 Dec 1;81(1):1