Sequence Detail

ID/Version

Q61091 A2RTK9 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Frizzled-8; Short=Fz-8; Short=mFz8;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 685 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fzd8	frizzled class receptor 8	45	134	4	5

Sequence references in MGI

J:37068 Wang Y, et al., A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. J Biol Chem. 1996 Feb 23;271(8):4468-76
J:93897 Lu W, et al., Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth. Cell. 2004 Oct 1;119(1):97-108
J:113117 Nam JS, et al., Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. J Biol Chem. 2006 May 12;281(19):13247-57
J:114051 Yao R, et al., Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled. Biochem Biophys Res Commun. 2001 Aug 31;286(4):771-8
J:229368 Janda CY, et al., Structural basis of Wnt recognition by Frizzled. Science. 2012 Jul 6;337(6090):59-64