Sequence Detail

ID/Version

Q61093 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Cytochrome b-245 heavy chain; EC=1.-.-.-;AltName: Full=CGD91-phox;AltName: Full=Cytochrome b(558) subunit beta; Short=Cytochrome b558 subunit beta;AltName: Full=Heme-binding membrane glycoprotein gp91phox;AltName: Full=Neutro

Provider

SWISS-PROT

Sequence

Polypeptide 570 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cybb	cytochrome b-245, beta polypeptide	77	109	3	19

Sequence references in MGI

J:31649 Bjorgvinsdottir H, et al., Cloning of murine gp91phox cDNA and functional expression in a human X-linked chronic granulomatous disease cell line. Blood. 1996 Mar 1;87(5):2005-10
J:172364 Kim BH, et al., A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection. Science. 2011 May 6;332(6030):717-21
J:209569 Noubade R, et al., NRROS negatively regulates reactive oxygen species during host defence and autoimmunity. Nature. 2014 May 8;509(7499):235-9
J:224449 Graham DB, et al., Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst. Nat Commun. 2015;6:7838
J:241355 Thomas DC, et al., Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity. J Exp Med. 2017 Apr 03;214(4):1111-1128
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89