Sequence Detail

ID/Version

Q61129 B2RWX8 Q9WU07 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Complement factor I; EC=3.4.21.45;AltName: Full=C3B/C4B inactivator;Contains: RecName: Full=Complement factor I heavy chain;Contains: RecName: Full=Complement factor I light chain;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 603 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cfi	complement component factor i	9	99	3	12

Sequence references in MGI

J:31869 Minta JO, et al., cDNA cloning, sequencing and chromosomal assignment of the gene for mouse complement factor I (C3b/C4b inactivator): identification of a species specific divergent segment in factor I. Mol Immunol. 1996 Jan;33(1):101-12
J:54388 Yun YS, et al., Cloning and characterization of the non-catalytic heavy chain of mouse complement factor I gene: structure comparison with the human homologue. Biochem Mol Biol Int. 1999 Mar;47(3):493-500
J:131403 Rose KL, et al., Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. J Clin Invest. 2008 Feb;118(2):608-18
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89